Above all else, we're left with no firm resolution on Pietro and Wanda's origins. They apparently accept the High Evolutionary's story that they're the children of Django and Marya Maximoff and that he altered their genetic structures to give them their powers. But, his story is full of all sorts of holes. For example, we're not told why he chose the Maximoffs in the first place or why he gave the twins the powers that he did. The Vision hints at "hidden truths" that he gleaned from reading the Evolutionary's files and they presumably fill in these gaps. However, he decides not to share said truths with Wanda because he fears that they will break here. If Remender had accomplished anything good in this short series, this part would've overshadowed it, since he just reverted Wanda to a character that he himself had thankfully put to rest. She had become such a stronger character under him, and it's hard to understand why he would leave her as essentially the "Avengers Disassembled" version of herself here.
But, the whole point of this series is that you shouldn't take it on its own merits. Its goal was clearly to ret-con the twins' history so that they were no longer mutants and thus so that Marvel could use them in its fight with Fox. If you go into this series with that approach, then it all makes sense. In fact, it suddenly makes sense why the Vision doesn't reveal the truth, because the truth itself is irrelevant. It also doesn't matter that Vision had a blink-and-you'll-miss-it relationship (and children) with some sort of android or that Brother Voodoo, Cap, Rogue, and Sabretooth could've almost literally been any other characters for all the impact that they have. This series is a means to that end and, unfortunately, little more.
** (two of five stars)